4-chloro-3-indolecarboxylic acid

4-chloro-3-indolecarboxylic acid - Names and Identifiers

Name	4-Chloro-1H-indole-3-carboxylic acid
Synonyms	4-CHLOROINDOLE-3-CARBOXYLIC ACID 4-Chloroindole-3-Carboxylic Acid 4-chloro-3-indolecarboxylic acid 4-chloro-1H-indole-3-carboxylic acid 4-Chloro-1H-indole-3-carboxylic acid 1H-INDOLE-3-CARBOXYLIC ACID,4-CHLORO 1H-indole-3-carboxylic acid, 4-chloro-
CAS	23872-36-8
InChI	InChI=1/C9H6ClNO2/c10-6-2-1-3-7-8(6)5(4-11-7)9(12)13/h1-4,11H,(H,12,13)

4-chloro-3-indolecarboxylic acid - Physico-chemical Properties

Molecular Formula	C9H6ClNO2
Molar Mass	195.6
Density	1.548±0.06 g/cm3 (20 ºC 760 Torr)
Boling Point	449.7±25.0 °C(Predicted)
Flash Point	225.8°C
Vapor Presure	7.12E-09mmHg at 25°C
pKa	2.43±0.10(Predicted)
Storage Condition	Sealed in dry,Room Temperature
Refractive Index	1.728

4-chloro-3-indolecarboxylic acid - Introduction

acid is an organic compound with the chemical formula C9H6ClNO2. It is a solid, room temperature and pressure for white to light yellow crystal. The following is a description of its nature, use, preparation and safety information:

Nature:
-Appearance: White to light yellow crystal
-Molecular weight: 195.60g/mol
-Melting point: About 228-230 ° C
-Solubility: Soluble in most organic solvents, such as alcohols, ethers and ketones, slightly soluble in water.

Use:
-sulfuric acid can be used as an important intermediate in organic synthesis, and is often used in the synthesis of various drugs and pesticides.
-It can also be used to prepare dyes, photoactive materials and chemical sensors.

Method:
acid can be synthesized by a variety of methods. The following is a common synthesis method:
1. First, 4-chloroindole is reacted with triethylamine to generate the corresponding salt.
2. Next, the salt is esterified using pyruvic acid to form a potassium acid ester.
3. Finally, the ester is reduced to acid by hydrolysis reaction.

Safety Information:
The acid is relatively stable when used under safe operation, but the following matters still need to be paid attention:
-It may be irritating to the skin, eyes and respiratory system and requires appropriate protective measures, such as wearing protective gloves, goggles and masks.
-Avoid inhaling its dust and maintain a well-ventilated working environment.
-When storing and handling, keep away from ignition and oxidizing agents to avoid fire or explosion.

Last Update：2024-04-09 21:01:54